According to a study published this month in the Frontiers in Veterinary Science journal, CBD was well tolerated by healthy dogs at a dose of 5 milligrams per kilogram of body weight. The first-of-its kind study included 16 male and 16 female beagles which were dosed for 90 consecutive days with a 14-day recovery period.
In a statement, National Animal Supplement Council (NASC) President Bill Bookout said the data demonstrates “that different cannabidiols are safe for long-term use in healthy dogs when given at the dose studied.”
“With safety studies, no matter how well controlled or meticulously defined, it is impossible to account for everything that can occur when a product is commercialized. That is why this safety study includes not only data from a well-designed study protocol, but also 10 years of post-market surveillance data from the NASC Adverse Event Reporting Database, which is the most advanced monitoring system in the world for these types of products given to companion animals. No other study that we are aware of is as comprehensive and includes both data sets.” — Bookout in a press release
The canines included in the study were randomized into four groups and treated with either medium chain triglyceride oil as the placebo and control or either broad spectrum CBD, broad spectrum CBD with cannabigerol (CBG), or broad spectrum CBD with cannabidiolic acid (CBDA), at a dose of 5 milligrams total cannabinoids. All animals completed the study which found that CBD, CBD plus CBG, and CBD plus CBDA at the ratios and doses utilized were well tolerated over the duration of the study period when healthy male and female beagles were dosed for 90 consecutive days.
The researchers noted that in the U.S. pet supplements are “unapproved animal drugs and available to consumers either through State-level regulations or enforcement discretion” by the Food and Drug Administration. According to NASC data, there were 274,129,622 administrations, in dogs, of hemp and hemp derivative products sold in 2022.
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